Hellboy and a rookie B.P.R.D. agent in the 1950s are sent to the Appalachians, where they discover a remote community dominated by witches and led by the sinister local demon, the Crooked Man.

1956 in France, a priest is horribly murdered. An evil is spreading. Once again, Sister Irene comes face-to-face with Valak, the demon nun.

Based on the true story of how the Norwegian crown princess steals the heart of President Franklin D. Roosevelt during World War II and changes the face of world politics.